1. (1)
Potential energy source, (2) Mechanism for converting potential energy
to kinetic energy and (3) Ability to use kinetic energy for mobility and a
therapeutic benefit
4. Their system is based on rotaxane, which is a
mechanically-interlocked molecular compound consisting of a dumbbell-shaped
molecule threaded through a ring. It is
a linear molecular motor powered exclusively by visible light and exhibits
autonomy by relying on intramolecular processes. The motor consists of an electron donor macrocycle
ring enclosed around a dumbbell-shaped dual electron acceptor. The overall length of the system is ~5nm and
the distance between the two electron acceptor sites is ~1.3nm. A photosensitizer drives electron transfer
upon exposure of the system to visible light and powers rotaxane shuttling. Three features include: (1) Powered by visible light; (2) Operates
autonomously; (3) No waste product generation.
7. The casing is composed of a silicon shell terminated
by sulfur. Each of nine separate planet
gears is attached to the planet carrier by a carbon-carbon single bond. The gear would convert shaft power from one
angular frequency to another.
10. Atom relay
13. Leonard Adelman used fragments of DNA to
compute the solution to a complex graph theory known as a Hamiltonian path
problem. Adleman's method utilized the
unique identities of the molecular subunits to represent the vertices of a
network. Combinations of these sequences
formed randomly during large-scale parallel reactions in a test tube and thus
represented random paths through the network or graph. Adleman was able to subsequently extract the
correct answer to the graph theory from the plethora of random paths
represented by the final product DNA strands.
16. Soluble thin films degrade in the presence of
plasma water to expose a sticky mesh complementary to blood group antigens
present on the surfaces of RBCs. This allows
for trapping of the red blood cells to create a netting composed of both cells
and mesh to halt bleeding.
19. The plasmonic nanobubbles combine optical
scattering for diagnosis with intracellular mechanical damage of target cells
for therapy. The system works by
clustering gold nanoparticles around molecular targets within cancer cells
followed by exposure to a laser pulse, which results in light scattering by
small PNBs and mechanical damage to cells via expansion and contraction of
larger PNBs. Thus simultaneous detection
and eradication of cancer cells is accomplished.
22. The grooves are designed to provide pathways
for the growth of regenerative axons.
They also limit the number of neuronal fibers that come into contact
with the longitudinal electrodes.